Clinical and Genetic Features of Coxiella burnetii in a Patient with an Acute Febrile Illness in Korea.
10.3346/jkms.2017.32.6.1038
- Author:
Seung Hun LEE
1
;
Jung Yeon HEO
;
Hae Kyung LEE
;
Yeong Seon LEE
;
Hye Won JEONG
;
Seon Do HWANG
Author Information
1. Division of Zoonoses, Center for Immunology & Pathology, Korea National Institute of Health, Korea Centers for Disease Control & Prevention, Cheongju, Korea. hwangsd@korea.kr
- Publication Type:Brief Communication
- Keywords:
Coxiella burnetii;
Q Fever;
Korea;
16s rRNA
- MeSH:
Adult;
Base Sequence;
Coxiella burnetii*;
Coxiella*;
Diagnosis;
Fluorescent Antibody Technique, Indirect;
Humans;
Korea*;
Q Fever;
Seroconversion;
Zoonoses
- From:Journal of Korean Medical Science
2017;32(6):1038-1041
- CountryRepublic of Korea
- Language:English
-
Abstract:
Although Q fever is an important zoonotic infection with a worldwide distribution, no human isolates of Coxiella burnetii have been identified in Korea. For the first time, we identified the nucleotide sequence of C. burnetii from a 32-year-old man with an acute febrile illness in Korea. Diagnosis of acute Q fever was confirmed by seroconversion using indirect immunofluorescence antibody assays. Phylogenetic analysis demonstrated high sequence similarity (99.6%–100%) with C. burnetii 16S rRNA sequences identified from the reservoir. These results are the first genetic analysis of C. burnetii in a human case of Q fever in Korea.
