Pulp response of mineral trioxide aggregate, calcium sulfate or calcium hydroxide.
10.5395/JKACD.2007.32.2.095
- Author:
Young Ran YUN
1
;
In Seok YANG
;
Yun Chan HWANG
;
In Nam HWANG
;
Hong Ran CHOI
;
Suk Ja YOON
;
Sun Hun KIM
;
Won Mann OH
Author Information
1. Department of Conservative Dentistry, DSRI, 2nd stage of BK21, School of Dentistry, Chonnam National University, Korea. wmoh@chonnam.ac.kr
- Publication Type:Original Article
- Keywords:
MTA;
Calcium sulfate;
Calcium hydroxide;
Pulp capping
- MeSH:
Anesthesia, General;
Animals;
Calcium Hydroxide*;
Calcium Sulfate*;
Calcium*;
Citric Acid;
Dental Pulp;
Dental Pulp Capping;
Dentin;
Dogs;
Eosine Yellowish-(YS);
Formaldehyde;
Humans;
Infant;
Inflammation;
Neutrophils;
Odontoblasts;
Pulp Capping and Pulpectomy Agents;
Tooth;
Pemetrexed
- From:Journal of Korean Academy of Conservative Dentistry
2007;32(2):95-101
- CountryRepublic of Korea
- Language:English
-
Abstract:
This study was performed to verify the possibility of MTA and calcium sulfate as a pulp capping agent through comparing the dental pulp response in dogs after capping with MTA, calcium sulfate, and calcium hydroxide. 24 teeth of 2 dogs, 8 month old, were used in this study. Under general anesthesia, cervical cavities were prepared and pulp was exposed with sterilized #2 round bur in a high speed handpiece. MTA, calcium hydroxide, and calcium sulfate were applied on the exposed pulp. Then the coronal openings were sealed with IRM and light-cured composite. Two months after treatment, the animals were sacrificed. The extracted teeth were fixed in 10% neutral-buffered formalin solution and were decalcified in formic acid-sodium citrate. They were prepared for histological examination in the usual manner. The sections were stained with haematoxylin and eosin. In MTA group, a hard tissue bridges formation and newly formed odontoblasts layer was observed. There was no sign of pulp inflammatory reaction in pulp tissue. In calcium hydroxide group, there was no odontoblast layer below the dentin bridge. In pulpal tissue, chronic inflammatory reaction with variable intensity and extension occurred in all samples. In calcium sulfate group, newly formed odontoblast layer was observed below the bridge. Mild chronic inflammation with a few neutrophil infiltrations was observed on pulp tissue. These results suggest that MTA is more biocompatible on pulp tissue than calcium hydroxide or calcium sulfate.
