Assessment of Attenuation Correction Techniques with a 137Cs Point Source.
- Author:
Jung Kyun BONG
1
;
Hee Joung KIM
;
Hye Kyoung SON
;
Yun Young PARK
;
Hae Joung PARK
;
Mijin YUN
;
Jong Doo LEE
;
Hae Jo JUNG
Author Information
1. Division of Nuclear Medicine, Yonsei University College of Medicine, Korea. hjkim@yumc.yonsei.ac.kr
- Publication Type:Original Article
- Keywords:
Positron emission tomography;
Attenuation correction;
137Cs point source
- MeSH:
Brain;
Noise;
Nuclear Medicine;
Positron-Emission Tomography;
Skull
- From:Korean Journal of Nuclear Medicine
2005;39(1):57-68
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: The objective of this study was to assess attenuation correction algorithms with the 137Cs point source for the brain positron emission tomography (PET) imaging process. MATERIALS AND METHODS: Four different types of phantoms were used in this study for testing various types of the attenuation correction techniques. Transmission data of a 137Cs point source were acquired after infusing the emission source into phantoms and then the emission data were subsequently acquired in 3D acquisition mode. Scatter corrections were performed with a background tail-fitting algorithm. Emission data were then reconstructed using iterative reconstruction method with a measured (MAC), elliptical (ELAC), segmented (SAC) and remapping (RAC) attenuation correction, respectively. Reconstructed images were then both qualitatively and quantitatively assessed. In addition, reconstructed images of a normal subject were assessed by nuclear medicine physicians. Subtracted images were also compared. RESULTS: ELAC, SAC, and RAC provided a uniform phantom image with less noise for a cylindrical phantom. In contrast, a decrease in intensity at the central portion of the attenuation map was noticed at the result of the MAC. Reconstructed images of Jaszack and Hoffan phantoms presented better quality with RAC and SAC. The attenuation of a skull on images of the normal subject was clearly noticed and the attenuation correction without considering the attenuation of the skull resulted in artificial defects on images of the brain. CONCLUSION: the complicated and improved attenuation correction methods were needed to obtain the better accuracy of the quantitative brain PET images.