Posterior Reversible Encephalopathy Syndrome in a Patient with Lupus Nephritis.
10.4078/jkra.2010.17.2.177
- Author:
Hyun Kyung KIM
1
;
Hyoun Ah KIM
;
Eun Jung JANG
;
Chang Hee SUH
Author Information
1. Department of Allergy and Rheumatology, Ajou University Hospital, Ajou University School of Medicine, Suwon, Korea. chsuh@ajou.ac.kr
- Publication Type:Case Report
- Keywords:
Systemic lupus erythematosus;
Posterior reversible encephalopathy syndrome;
Lupus nephritis
- MeSH:
Antihypertensive Agents;
Blood Pressure;
Eclampsia;
Female;
Follow-Up Studies;
Headache;
Humans;
Hypertension;
Lupus Erythematosus, Systemic;
Lupus Nephritis;
Magnetic Resonance Spectroscopy;
Paresis;
Pregnancy;
Renal Dialysis;
Seizures
- From:The Journal of the Korean Rheumatism Association
2010;17(2):177-182
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Posterior reversible encephalopathy syndrome (PRES) has been described in various clinical settings, including severe hypertension, eclampsia, lupus and immunosuppressive therapy. We report a 27 year-old female systemic lupus erythematosus patient who developed severe headache, seizure and hemiparesis during her lupus nephritis flare. Magnetic resonance image (MRI) showed multi-focal high signal intensity lesions in the parieto-occipital cortex bilaterally and in the subcortical white matter. Her condition improved with immunosuppressive treatments, antihypertensives and hemodialysis. The extent of her lesions decreased on follow-up MRI 2 months later. This case suggests that PRES can be treated with immunosuppressive drugs that do not increase blood pressure.
