A case of lung metastasis of malignant eccrine poroma.
- Author:
Yoon Kyung PARK
1
;
Mi Ok KIM
;
Sung Soo PARK
;
Dong Ho SHIN
;
Ho Ju YOON
;
Jang Won SOHN
;
Chan Kum PARK
Author Information
1. Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea. lilychris@lycos.co.kr
- Publication Type:Case Report
- Keywords:
Porocarcinoma;
Lymphatic and hematogenous lung metastasis with pleural seeding
- MeSH:
Biopsy, Fine-Needle;
Bleomycin;
Drug Therapy;
Dyspnea;
Eccrine Porocarcinoma*;
Female;
Humans;
Lung*;
Lymph Nodes;
Middle Aged;
Neoplasm Metastasis*;
Neoplasms, Unknown Primary;
Pleura;
Pleural Effusion;
Pleurodesis;
Radiography, Thoracic;
Radiotherapy;
Skin;
Thoracic Wall;
Thorax
- From:Korean Journal of Medicine
2004;66(3):302-306
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Malignant eccrine poroma is a rare skin appendage tumor, originating from the intraepidermal and upper dermal eccrine ducts. It is a locally aggressive neoplasm with a high propensity to metastasize. A 47-year-old woman was admitted to the hospital because of dyspnea. One and half years before admission, she had been diagnosed porocarcinoma of left sole and treated with wide local excision. One months after excision, examination had revealed an inguinal lymph node metastasis and she had been treated with lymph node resection and radiotherapy. During the two weeks before admission, the patient had increasing exertional dyspnea, which was accompanied by Rt-sided chest wall pain. On admission right pleural effusion and multiple nodular densities were noted at initial chest radiograph. A computed tomographic (CT) scan of the chest showed lymphatic and hematogenous lung metastasis with pleural seeding of unknown primary tumor. Fine-needle aspiration biopsy of the pleura revealed typical cytologic findings of porocarcinoma. She was treated with therapeutic thoracentesis and pleurodesis with bleomycin. Because porocarcinoma is resistant to chemotherapy and radiotherapy, she has been treated with conservative treatment.
