A case of autoimmune hepatitis type-1 with p-ANNA strong positivity.
- Author:
Dong Seong JEONG
1
;
Je Hyuk CHUNG
;
Byoung Pyo KWON
;
Sang Jun AHN
;
Jin Seok JANG
;
Sang Young HAN
;
Kyung Hee KIM
Author Information
1. Department of Internal Medicine, Dong-A University College of Medicine, Busan, Korea. syhan@daunet.donga.ac.kr
- Publication Type:Case Report
- Keywords:
Autoimmune hepatitis;
p-ANNA
- MeSH:
Cholangitis, Sclerosing;
Diagnostic Tests, Routine;
Hepatitis;
Hepatitis, Autoimmune*;
Humans;
Korea;
Liver;
Liver Diseases
- From:Korean Journal of Medicine
2004;66(3):321-325
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Autoimmune hepatitis (AIH) is an undissolved inflammatory process of the liver characterized by the periportal hepatitis on histological examination and serum autoantibody. AIH seems to be partly responsible for chronic liver disease of unknown etiology in Korea. Perinuclear-Antineutrophil nuclear antibody (p-ANNA) are detected in up to 88% of patient with primary sclerosing cholangitis (PSC) and presence of p-ANNA in PSC makes them a reasonable diagnostic maker in conjuction with standard diagnostic test. But p-ANNA in AIH is rare and it's role remain unclear. We report the first case of 39 year-old-female patient with AIH type-1 with p-ANNA strong positivity.
