Effect of bamboo salt on human gingival fibroblasts.
10.11149/jkaoh.2014.38.2.90
- Author:
Han Na OH
1
;
Choong Ho CHOI
Author Information
1. Dental Hygiene, Wonkwang Health Science University, Chonnam National University School of Dentistry, Gwanju, Korea.
- Publication Type:Original Article
- Keywords:
Bamboo salt;
Human gingival fibroblast;
IL-1beta;
IL-6
- MeSH:
Bays;
Cytokines;
Fibroblasts*;
Humans;
Inflammation;
Interleukin-6;
Interleukins;
Real-Time Polymerase Chain Reaction
- From:Journal of Korean Academy of Oral Health
2014;38(2):90-94
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVES: To evaluate the anti-inflammatory and cytotoxic activities of bamboo salt. METHODS: Cytotoxicity of bamboo salt and bay salt (0.01%, 0.1%, and 1%) was evaluated using MTT assay. In addition, secretion of the pro-inflammatory cytokines interleukin (IL)-1beta and IL-6 from human gingival fibroblasts (HGFs) was measured after application of 0.01% and 0.1% concentrations by using real-time polymerase chain reaction. RESULTS: Bamboo salt and bay salt at 1% concentration were cytotoxic to HGFs at 24 h; however, no such effect was observed at 0.01% or 0.1%. Bamboo salt showed a relatively low inhibitory effect. IL-1beta secretion was inhibited by a 0.1% solution of bamboo salt. IL-6 secretion was inhibited by both bamboo salt and bay salt at 0.1% concentration. CONCLUSIONS: The above results suggest that bamboo salt inhibits the release of IL-1beta and IL-6 from HGFs. Thus, bamboo salt may be a useful material for gingival inflammation.
