Predictive factors of restenosis after stenting in proximal left anterior descending coronary artery.
- Author:
Seung Hyun LEE
1
;
Myung Ho JEONG
;
Doo Sun SIM
;
Sang Hyun LEE
;
Young Joon HONG
;
Ok Young PARK
;
Woo Seok PARK
;
Ju Han KIM
;
In Soo KIM
;
Myung Ja CHOI
;
Weon KIM
;
Young Keun AHN
;
Jeong Gwan CHO
;
Jong Chun PARK
;
Jung Chaee KANG
Author Information
1. The Heart Center of Chonnam National University Hospital, Chonnam National University Research Institute of Medical Sciences, Gwangju, Korea. myungho@chollian.net
- Publication Type:Original Article
- Keywords:
Coronary Diseases;
Stents;
Restenosis
- MeSH:
Atherosclerosis;
Constriction, Pathologic;
Coronary Disease;
Coronary Vessels*;
Diagnosis;
Follow-Up Studies;
Humans;
Incidence;
Ischemic Attack, Transient;
Jeollanam-do;
Myocardial Infarction;
Percutaneous Coronary Intervention;
Phenobarbital;
Risk Factors;
Stents*;
Stroke
- From:Korean Journal of Medicine
2003;65(3):300-307
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: A proximal Left anterior descending coronary artery (LAD) is one of the most important arterial segment due to its wide area of myocardial blood supply and high incidence of restenosis after percutaneous coronary intervention. This study was aimed to predict the risk factor after stenting in proximal LAD. METHODS: A total of 412 patients with proximal LAD stent implantation, who underwent follow-up coronary angiogram except for the LAD ostial lesion between 1996 and 2001 at Chonnam National University Hospital, were divided into two groups: Restenosis group (n=144 : 57.5 +/- 10.2 years, 78.8% male) and no restenosis group (n=268 : 57.4 +/- 10.0 years, 76.8% male). Restenosis rate, complications and predictive factors after proximal LAD stenting were analyzed. RESULTS: There were no differences in baseline clinical characteristics of sex, age, risk factors of atherosclerosis, lipid profile, clinical diagnosis, type and number of lesion coronary artery, Thrombolysis In Myocardial Infarction flow between the two groups. The restenosis rate after proximal LAD stenting was 35.0%. The complications during the follow up period after stenting were one transient ischemic attack in restesnosis group and one non-hemorrhagic stroke in both groups. There were no differences in major advanced cardiac event until the 12th month clinical follow up. There were no differences in lesion length, reference diameter, minimal luminal diameter, diameter stenosis and stent diameter, but the stent length were longer (20.7 +/- 6.92 mm) in restenosis group compared with no restenosis group (18.8 +/- 6.18 mm, p=0.006). CONCLUSION: The restenosis rate after proximal LAD stenting is relatively high and the only predictive factor for restenosis is stent length.
