Corneal Endothelial Changes after Laser Assisted In Situ Keratomileusis.
- Author:
Heon Seung HAN
1
;
Hai Ryun JUNG
;
Hyo Myung KIM
Author Information
1. Department of Ophthalmology, College of Medicine, Korea University.
- Publication Type:Original Article
- Keywords:
Corneal endotheliu;
High myopia;
LASIK;
Residual corneal thickness
- MeSH:
Cell Count;
Endothelial Cells;
Endothelium, Corneal;
Follow-Up Studies;
Keratomileusis, Laser In Situ;
Myopia
- From:Journal of the Korean Ophthalmological Society
1997;38(9):1510-1516
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Laser assisted in situ keratomileusis(LASIK) is a widely used technique for correcting high myopia. Its technical methods and excellent clinical results are well known, but its potential risk on the corneal endothelium are poorly known. We used specular microscope to underwent LASIK for the correction of myopia. The mean preoperative refraction was ?4.5 diopters (range, -10.00 to -23.50 diopters.). The average endothelial cell densities were 2,817+/-205 cells/mm2 (mean +/-SD) preoperatively and 2,789+/-211 cells/mm2 3 months postoperatvely, corresponding to fall of 28 cells/mm2. This fall in endothelial cell density was not statistically significant (P>0.05). But significant correlation between the change in cell density and the residual corneal thickness was found(P>0.05). These results suggest that LASIK is a predictable and safe method for correcting high myopia, but care is recommended when doing deep corneal ablation. Long term follow-up may be needed to confirm its safety.