Benign Histiocytoma of the Lung: A Case Report.
- Author:
Myoung Ja CHUNG
1
;
Min Ho KIM
;
Hyun Jin SON
Author Information
1. Department of Pathology, Chonbuk National University Medical School, Jeonju, Korea. shjpathol@hotmail.com
- Publication Type:Case Report
- Keywords:
Histiocytoma;
Lung
- MeSH:
Actins;
Cytoplasm;
Diagnosis, Differential;
Eosinophils;
Histiocytoma*;
Humans;
Keratins;
Lung*;
Middle Aged;
Muscle, Smooth;
Solitary Pulmonary Nodule;
Thoracotomy;
Tomography, X-Ray Computed;
Vimentin
- From:Korean Journal of Pathology
2005;39(5):351-355
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Histiocytomas have rarely been reported in the lungs. We report an unusual benign pulmonary histiocytoma in a 45-year-old man and discuss the differential diagnosis. Chest CT showed a well-defined solitary pulmonary nodule of approximately 3 cm in size in the posterobasal segment of the right lower lobe. Posterolateral thoracotomy and wedge resection was performed. Gross examination revealed a mass, measuring 2.2 x 2.1 cm that had a circumscribed margin within the lung parenchyma. Microscopically, the tumor was entirely composed of large polygonal to round cells with a few chronic inflammatory cells. These tumor cells contained abundant cytoplasm which was either granular, eosinophilic or foamy. Immunohistochemically, these cells were diffusely positive for CD68 and focally positive for 1-antitrypsin, but negative for cytokeratin, vimentin, and smooth muscle actin.
