Subclinical Vitamin D Insufficiency in Korean School-aged Children.
10.5223/pghn.2013.16.4.254
- Author:
Sang Woo HAN
1
;
Ha Ra KANG
;
Han Gyum KIM
;
Joo Hyun KIM
;
Ji Hyun UHM
;
Ji Young SEO
Author Information
1. Department of Pediatrics, Eulji General Hospital, Seoul, Korea. pedseo@eulji.ac.kr
- Publication Type:Original Article
- Keywords:
Vitamin D;
25 Hydroxy vitamin D3;
Vitamin D insufficiency;
Child;
Body mass index
- MeSH:
Adolescent;
Body Mass Index;
Body Weight;
Child*;
Cholecalciferol;
Comorbidity;
Hospitals, General;
Humans;
Korea;
Outpatients;
Pediatrics;
Prevalence;
Puberty;
Retrospective Studies;
Sunlight;
Vitamin D*;
Vitamins*
- From:Pediatric Gastroenterology, Hepatology & Nutrition
2013;16(4):254-260
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: Recently, vitamin D insufficiency has increased and has been correlated to growth and puberty in children. This study was conducted to find the prevalence of subclinical vitamin D insufficiency and its influence on school-aged children in Korea. METHODS: The subjects of this study were 397 children aged 7 to 15 years who had been tested for 25-OH vitamin D3 among the outpatients of the Department of Pediatrics in Eulji General Hospital from March 2007 to February 2011. Data for age, sex, comorbidities, serum 25-OH vitamin D3, height, weight, body mass index (BMI), and sunlight exposure time were collected before and after 3 months of vitamin D administration, retrospectively. RESULTS: Vitamin D insufficiency was present in 343 (86%) of the subjects. In the vitamin D insufficient group, chronological age was 8.96+/-1.72 years, mean height (z-score [z]) was 0.51+/-1.26, mean BMI (z) was 0.81+/-2.20, and bone age was 10.26+/-1.75 years. In the vitamin D sufficient group, chronological age was 9.61+/-1.77 years, mean height (z) was-0.66+/-0.98, mean BMI (z) was-0.01+/-1.16, and bone age was 9.44+/-2.12 years. A paired t-test showed that three months after vitamin D administration, the mean 25-OH vitamin D3 level in the insufficient group increased to 24.38 +/-10.03 ng/mL and mean BMI (z) decreased to 0.67+/-1.06. CONCLUSION: In Korean school-aged children, vitamin D insufficiency were relatively higher and may be closely related with higher BMI. Insufficient rise of the level of vitamin D after supplementation suggest the new supplementation guidelines, especially for Korean children.
