A case of autoimmune neutropenia.
- Author:
Cheol Su POO
1
;
Hyun Jang CHO
;
Ji Soo KIM
;
Yang Seung HO
;
Heon Jik LEE
;
Du Hyung KIM
;
Yong Seok YANG
;
Seung Young KIM
;
Byeung Yub PARK
Author Information
1. Department of Internal Medicine, Hae dong Hospital, Pusan, Korea.
- Publication Type:Case Report
- Keywords:
autoimmune neutropenia;
cell-bound neutrophil antibodies
- MeSH:
Antibodies;
Autoimmune Diseases;
Diagnosis;
Fluorescent Antibody Technique, Indirect;
Gastrectomy;
Humans;
Joint Diseases;
Korea;
Neutropenia*;
Neutrophils;
Stomach Neoplasms
- From:Korean Journal of Medicine
1998;55(5):965-970
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Autoimmune neutropenia is characterized by severe neutropenia with cell-bound neutrophil antibodies or circulating antibodies for neutrophils. Diagnosis of disease is made of the basis of the presence of antibodies for neutrophil. Corticosteroid or rhG-CSF have been reported to be effective in some patients. Recently we experienced one case of autoimmune neutropenia patient who was admitted to our hospital in 1997 because of stomach cancer and degenerative joint disease. She had severe neutropenia without underlying autoimmune disease. And cell-bound neutrophil antibodies were detected by indirect immunofluorescence test. Treatments with rhG-CSF and steroid result in transient improvement of neutropenia and subtotal gastrectomy was done successfully. We herein report one case of autoimmune neutro- penia patient, to our best knowledge, the first report in Korea, with a brief review of literature.
