Malignant Peripheral Nerve Sheath Tumor Arising from Neurofibromatosis.
10.5021/ad.1996.8.2.153
- Author:
Seog Jun HA
;
Young Min PARK
;
Jong Yuk YI
;
Tae Yoon KIM
;
Chung Won KIM
;
Jung Yong LEE
;
Seok Jin KANG
- Publication Type:Case Report
- Keywords:
Electron microscopic study;
Malignant peripheral nerve sheath tumor;
Neurofibromatosis
- MeSH:
Aged;
Cytoplasm;
Female;
Glycogen;
Humans;
Intercellular Junctions;
Intermediate Filaments;
Microscopy, Electron;
Neurofibromatoses*;
Neurofibromatosis 1;
Peripheral Nerves*;
Thorax
- From:Annals of Dermatology
1996;8(2):153-157
- CountryRepublic of Korea
- Language:English
-
Abstract:
A 65-year-old woman complained of a pedunculated, huge mass on the anterior chest associated with neurofibromatosis type 1. The clinical and histological data showed the possibility of a malignant peripheral nerve sheath tumor. On electron microscopy, we found the characteristic findings of a malignant peripheral nerve sheath tumor, such as the foci of en-tangled cytoplasmic processes, undifferentiated spindle cells having large pleomorphic nuclei with prominent nucleoli, distinct basal cell lamina, rudimentary cell junctions, intermediate filaments and clumps of glycogen in the tumor cells. We, herein, report a case of malignant peripheral nerve sheath tumor arising from neurofibromatosis, studied by electron microscopy.
