Goals of Treatment, Indication, and Treatment for Chronic Hepatits C.
- Author:
Seung Woon PAIK
1
Author Information
1. Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. sw.paik@samsung.com
- Publication Type:Review ; English Abstract
- Keywords:
Hepatitis C;
Pegylated interferon;
Ribavirin
- MeSH:
Antiviral Agents/*therapeutic use;
Drug Therapy, Combination;
Hepatitis C, Chronic/diagnosis/*drug therapy;
Humans;
Interferon Alfa-2a/*therapeutic use;
Interferon Alfa-2b/*therapeutic use;
Polyethylene Glycols/*therapeutic use;
Ribavirin/*therapeutic use
- From:The Korean Journal of Gastroenterology
2008;51(6):368-371
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Hepatitis C virus (HCV) is a major cause of chronic hepatitis and hepatic fibrosis worldwide. Up to 85% of individuals infected with HCV develop chronic infection, which can progress to cirrhosis and hepatocellular carcinoma. The primary goal in the treatment of HCV infection is to reduce the mortality by preventing liver-related deaths associated with the development of hepatocellular carcinoma and decompensated cirrhosis. Pegylated interferons together with ribavirin are currently the standard of care for patients with chronic hepatitis. Here, I discuss the goals of treatment, indication and treatment of chronic hepatitis C.