A Case of Vanishing Bile Duct Syndrome Associated with Ibuprofen Overuse.
- Author:
Gook Chan JANG
1
;
Kyung Rye MOON
;
Chae Hong SUH
Author Information
1. Department of Pediatrics, College of Medicine, Chosun University, Gwangju, Korea. krmoon@mail.chosun.ac.kr
- Publication Type:Case Report
- Keywords:
Vanishing bile duct syndrome;
Ibuprofen
- MeSH:
Bile Ducts*;
Bile*;
Biopsy;
Eosinophilia;
Exanthema;
Fever;
Humans;
Ibuprofen*;
Jaundice;
Korea;
Liver;
Male;
Xanthomatosis
- From:Korean Journal of Pediatric Gastroenterology and Nutrition
2006;9(2):262-268
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Ibuprofen is currently widely prescribed in the pediatric population and has potentially very severe adverse events, even in the absence of an overdose. We treated a four year-old male who presented with severe jaundice, skin rash, xanthoma, eosinophilia and decreased hepatic function after overuse of ibuprofen for fever control. The liver biopsy revealed the vanishing bile duct syndrome. We report a case of vanishing bile duct syndrome associated with Ibuprofen overuse for the first case in Korea.
