Optic Cup Slope as a Numeric Representative of Glaucomatous Cupping.
10.3341/jkos.2013.54.3.462
- Author:
Sang Il AHN
1
;
Jee Ho CHANG
Author Information
1. Department of Ophthalmology, Soonchunhyang University College of Medicine, Bucheon, Korea. jhchang@schmc.ac.kr
- Publication Type:Original Article
- Keywords:
Cup slope;
Disc cup;
Glaucoma;
OCT
- MeSH:
Eye;
Glaucoma;
Humans;
ROC Curve;
Visual Field Tests;
Visual Fields
- From:Journal of the Korean Ophthalmological Society
2013;54(3):462-468
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To objectively define the degree of cupping, the authors extracted 3-dimensional slope surface maps from Cirrus HDTM-OCT data and assessed their differentiating characteristics between normal subjects and glaucomatous patients. METHODS: One eye from each of 40 normal subjects and 1 eye from each of 39 patients with glaucoma were examined using automated visual field perimetry and Cirrus HDTM-OCT. The Optic Disc Cube 200 x 200 protocol was performed. The individual OCT data were reconstructed as the 3-dimensional surface maps of the optic disc cup and the slope of each contour was calculated using custom-developed software. Several disc cup slope parameters were derived. The parameters measuring the internal features of the optic disc cup were calculated and compared between groups. RESULTS: Sum of cup slope, sum of thresholded cup slope, and sum of thresholded cup slope / thresholded cup area parameters were differentiating factors between the normal and glaucoma groups (p < 0.05). The area under the receiver operating characteristic curve (AUROC) value of the slope parameters ranged from 0.718 to 0.753. The sum of thresholded cup slope / thresholded cup area parameter was well correlated with visual field mean deviation (r = -0.250, p = 0.028). CONCLUSIONS: The optic disc cup slope parameter obtained with OCT may be a useful parameter for representing glaucomatous cupping.
