Whole Blood and Plasma Vitamin C Concentrations in Children of 1-6 Years of Age in the Chinju Area.
- Author:
Hyang Ok WOO
1
;
Jin Su JUN
;
Ji Hoe PARK
;
Young Suk KIM
;
Eun A KIM
;
Jae Young LIM
;
Myoung Bum CHOI
;
Chan Hoo PARK
;
Hee Shang YOUN
;
Gyung Hyuck KO
;
Seung Chul BAIK
;
Woo Kon LEE
;
Myung Je CHO
;
Kwang Ho RHEE
Author Information
1. Department of Pediatrics, Gyeongsang National University College of Medicine, Chinju, Korea.
- Publication Type:Original Article
- Keywords:
Whole blood;
Plasma;
Vitamin C;
Antioxidant;
Child
- MeSH:
Antioxidants;
Ascorbic Acid Deficiency;
Ascorbic Acid*;
Child*;
Female;
Gyeongsangnam-do*;
Humans;
Male;
Plasma*;
Vitamins*
- From:Journal of the Korean Pediatric Society
2001;44(5):501-508
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: Vitamin C among antioxidants in human is a physiological antioxidant for protection against diseases. We measured the vitamin C concentrations of whole blood and plasma among children in early childhood at normal condition in order to know the presence of vitamin C deficiency. METHODS: The venous blood was collected from 471 subjects at 1-6 years of ages in Chinju. Concentrations of vitamin C in whole blood and plasma were measured by the 2,4-dinitrophenylhydrazine method. RESULTS: Concentrations of vitamin C in whole blood and plasma were 1.68mg/dL and 0.94mg/dL, respectively. While concentrations of vitamin C in the whole blood and plasma of males were 1.69 mg/dL and 0.92mg/dL, respectively. Those of females, were 1.68mg/dL and 1.00mg/dL, respectively. The concentrations did not significantly differ by gender. Concentrations of vitamin C in plasma were positively correlated with the age of the entire study group and of female(P=0.01). Percentages of subjects with vitamin C concentrations of the whole blood less than 1.0mg/dL were 1.9%, and those of the plasma of below 0.6mg/dL were 20.6%. CONCLUSION: Concentrations of vitamin C in whole blood and plasma did not show normal distribution. And there were no relationship among age, gender, and vitamin C concentrations at early childhood. A significant number of children in Chinju had suboptimal plasma vitamin C concentration. These findings suggest a need for an increased vitamin C intake in this area.
