Remifentanil-Propofol Sedation as an Ambulatory Anesthesia for Carpal Tunnel Release.
10.3340/jkns.2010.48.5.429
- Author:
Jae Jun LEE
1
;
Sung Mi HWANG
;
Ji Su JANG
;
So Young LIM
;
Dong Hwa HEO
;
Yong Jun CHO
Author Information
1. Department of Anesthesiology and Pain Medicine, Chuncheon Sacred Heart Hospital, School of Medicine, Hallym University, Chuncheon, Korea.
- Publication Type:Original Article
- Keywords:
Carpal tunnel syndrome;
Propofol;
Remifentanil
- MeSH:
Anesthesia;
Anesthesia, Local;
Anesthetics, Local;
Anxiety;
Carpal Tunnel Syndrome;
Humans;
Incidence;
Patient Satisfaction;
Piperidines;
Propofol;
Prospective Studies;
Vomiting
- From:Journal of Korean Neurosurgical Society
2010;48(5):429-433
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVE: This prospective study evaluated the use of continuous sedation using propofol and remifentanil when carpal tunnel release (CTR) was performed under local anesthesia. METHODS: We sedated 60 patients undergoing CTR using local anesthesia with remifentanil at loading and continuous doses of 0.5 microg kg(-1) and 0.05 microg kg(-1)min(-1), respectively, and propofol, using a target controlled infusion (TCI) pump set to a target of 2 microg mL(-1) (group A), or with the same drug doses except that the continuous remifentanil dose was 0.07 microg kg(-1)min(-1) (group B) or 0.1 microg kg-1min-1 (group C). RESULTS: In group B, the levels of pain when local anesthetics were administered (p = 0.001), intraoperative pain (p < 0.001) and anxiety (p = 0.001) were significantly lower than those of group A. Furthermore, the incidence of adverse events, including desaturation (p < 0.001) and vomiting (p = 0.043), was significantly lower in group B than in group C. CONCLUSION: Continuous sedation using an appropriate dose of remifentanil and propofol can be used as safe, efficacious ambulatory anesthesia in cases of CTR under local anesthesia, performed using only 2 mL of local anesthetic, with a high degree of patient satisfaction.