A Case of Idiopathic Adulthood Ductopenia.
10.3904/kjim.2009.24.3.270
- Author:
Byeong Chool PARK
1
;
Seon Mee PARK
;
Eun Young CHOI
;
Hee Bok CHAE
;
Se Jin YOON
;
Rohyun SUNG
;
Sung Koo LEE
Author Information
1. Department of Internal Medicine, Chungbuk National University College of Medicine and Medical Research Institute, Cheongju, Korea. smpark@chungbuk.ac.kr
- Publication Type:Case Report ; Research Support, Non-U.S. Gov't
- Keywords:
Idiopathic adulthood ductopenia;
Cholestasis
- MeSH:
Adult;
Cholestasis, Intrahepatic/*diagnosis/etiology/pathology;
Chronic Disease;
Humans;
Male
- From:The Korean Journal of Internal Medicine
2009;24(3):270-273
- CountryRepublic of Korea
- Language:English
-
Abstract:
Idiopathic adulthood ductopenia (IAD) is a chronic cholestatic liver disease of unknown etiology characterized by adult onset, an absence of autoantibodies, inflammatory bowel disease, and a loss of interlobular bile ducts. In the present report, a case fulfilling the IAD criteria is described. A 19-year-old man was admitted to the hospital for persistent elevation of transaminases and alkaline phosphatase without clinical symptoms. Viral hepatitis markers and autoantibodies were absent. The patient had a normal extrahepatic biliary tree and had no evidence of inflammatory bowel disease. A liver biopsy specimen showed absence of interlobular bile ducts from 58% of the portal tracts. He was diagnosed with IAD and was treated with ursodeoxycholic acid.