Risk Factor Analysis for Development of Asymptomatic Carotid Stenosis in Koreans.
10.3346/jkms.2006.21.1.15
- Author:
Yun Jeong LIM
1
;
Young Wook KIM
;
Yeon Hyen CHOE
;
Chang Seok KI
;
Sue Kyung PARK
Author Information
1. Department of Internal Medicine, Dongguk University International Hospital, Dongguk University College of Medicine, Goyang, Korea.
- Publication Type:Original Article ; Comparative Study
- Keywords:
Carotid Stenosis;
Atherosclerosis;
Risk Factors
- MeSH:
Adult;
Age Factors;
Aged;
Carotid Stenosis/blood/*epidemiology/etiology;
Cholesterol/blood;
Comparative Study;
Female;
Humans;
Korea/epidemiology;
Lipoproteins, LDL Cholesterol/blood;
Logistic Models;
Male;
Middle Aged;
Multivariate Analysis;
Prevalence;
Retrospective Studies;
Risk Factors;
Smoking/adverse effects
- From:Journal of Korean Medical Science
2006;21(1):15-19
- CountryRepublic of Korea
- Language:English
-
Abstract:
Many risk factors for atherosclerosis have been proposed to identify high risk individuals. We conducted a retrospective study to determine the risk factors for development of carotid stenosis (CS) in Koreans. Database of 2,805 subjects who underwent a check up of carotid artery for health examination were analyzed. Stenosis (%) of common carotid artery or proximal internal carotid artery was examined with ultrasonography. Subjects were divided into 2 groups (Group I; CS <10%, Group II; CS > or =30%). We compared demographic, laboratory and clinical data between 2 groups to determine the risk factors of CS. One hundred ninety seven subjects (7.0%) were categorized as Group II. At age- and sex-adjusted multivariate analysis, diabetes mellitus, hypertension, cerebrovascular disease, ischemic heart disease, hyperlipidemia, aspirin medication, current smoking, fasting glucose, total cholesterol, low density lipoprotein-cholesterol (LDL-C) and leukocyte count were significant risk factors of CS. At stepwise logistic regression analysis, age, hypertension, hyperlipidemia, LDL-C and leukocyte count were independent risk factors. At subgroup analysis by smoking, age and leukocyte count were independent risk factors in smoker and age and hypertension in nonsmoker.
