Clinical Features of Morbilliform Erythema in Patients with Systemic Lupus Erythematosus.
- Author:
Jae Hong JUN
;
Chang Woo LEE
- Publication Type:Original Article
- Keywords:
Systemic lupus erythematosus;
Acute cutaneous lupus erythematorsus;
Morbilliform erythema;
Disease activity
- MeSH:
Autoantibodies;
Blister;
Erythema*;
Exanthema;
Extremities;
Humans;
Lupus Erythematosus, Systemic*;
Oral Ulcer;
Skin;
Skin Diseases
- From:Korean Journal of Dermatology
1998;36(2):236-240
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: In patients with systemic lupus erythematosus(SLE), LE-specific cutaneous lesions include malar rashes, widespread/morbilliform erythema, oral ulcer and bullous lesions. OBJECTIVE: Clinical observations were carried out to define cutaneous features of morbilliform erythema and to see possible relevancy of this erythema to disease activity of SLE. METHODS: Examinations were performed on 7 SLE patients with morbilliform erythema regarding the distribution and course of the cutaneous lesions; some SLE-activity related hematologic/immunologic data taken during/around the time of this skin disease were also assessed in each patient. RESULTS: In most of those patients with morbilliform erythema, which covered the trunk and extremities, the skin lesions lasted for about 2 weeks until their disappearance. At or around the time of suffering from this skin disease of acute eutaneous LE, activities of systemic disease were recognized as "in a state of flare-up or aggravation" with hypocomplementemia and high titers of anti-nDNA autoantibodies. CONCLUSION: As with malar rashes, morbilliform erythema of acute cutaneous LE seems to develop more frequently at the time of severe systemic involvement of immunopathological processes of SLE.
