Prenatal, Perinatal and Developmental Risk Factors of Attention-Deficit Hyperactivity Disorder.
10.5765/jkacap.2015.26.2.112
- Author:
Jin Young YEO
1
;
Sejin CHOI
;
Yeon Ho JOO
;
Hyo Won KIM
Author Information
1. Didim Psychiatric Clinic, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Attention-Deficit/Hyperactivity Disorder;
Developmental Risk Factors;
Perinatal Risk Factors;
Siblings
- MeSH:
Ambulatory Care Facilities;
Child;
Child Psychiatry;
Chungcheongnam-do;
Humans;
Parents;
Pregnancy;
Risk Factors*;
Siblings;
Surveys and Questionnaires
- From:Journal of the Korean Academy of Child and Adolescent Psychiatry
2015;26(2):112-119
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVES: The purpose of this study was to examine the prenatal, perinatal and developmental risk factors of attention-deficit hyperactivity disorder (ADHD), compared to unaffected siblings (SIB), and typically developing children (TC). METHODS: Subjects with ADHD, their SIB, and TC were recruited from the child psychiatry outpatient clinic of the Asan Medical Center Children's Hospital. The parents of the children completed questionnaires on perinatal and developmental risk factors. RESULTS: Fifty-eight subjects with ADHD (41 boys, 7.7+/-1.3 years), 21 SIB (8 boys, 8.2+/-1.8 years), and 22 TC (8 boys, 8.5+/-2.1 years) were included. The ADHD group showed higher rates of maternal stress during pregnancy than the SIB group (p=.002), and the ADHD group showed higher rates of familial psychiatric history than the TC (odds ratio, 8.76 ; 95% confidence interval, 1.69 to 45.45). CONCLUSION: These findings suggest that among perinatal and developmental factors, maternal stress during pregnancy contribute to the development of ADHD. Future prospective studies will be needed in order to determine the causal relationship between perinatal risk factors and development of ADHD.