Breast Cancer and Additional Primary Cancer : Two case reports.
- Author:
Seog Mo KIM
1
;
Kweon Cheon KIM
Author Information
1. Department of Surgery, Chosun University Hospital, Kwangju, Korea.
- Publication Type:Case Report
- Keywords:
Multiple primary malignant neoplasms;
Breast cancer
- MeSH:
Adenoma, Pleomorphic;
Breast Neoplasms*;
Breast*;
Female;
Humans;
Incidence;
Neoplasms, Second Primary;
Ovary;
Salivary Glands;
Thyroid Diseases;
Thyroid Gland
- From:Journal of the Korean Surgical Society
1998;54(Suppl):1032-1037
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The pathologic standards of multiple primary malignant neoplasms are : 1) Each tumor should be pathologically malignant. 2) Each tumor should be an independent malignancy, and not the result of submucosal or intraepidermal malignant changes. 3) Additional malignancies should not be metastatic. Multiple primary malignant neoplasms which have these standards have been studied continuously, no conclusive evidence for causal relationship has been established. Especially, many reports on the association of breast cancer with thyroid disease or salivary gland tumors have been published, but without any definite evidence. In 1984, Dr. Schenker, however, declared that during an 18-year study, 10,302 cases of breast carcinomas were diagnosed, and, of these, 984 patients(8%) had multiple primary malignant tumors. A significantly higher than expected incidence of second primary cancers occurred at the following five sites : the opposite breast, the salivary glands, the uterine corpus, the ovaries, and the thyroid. The authors report one example of Grave's disease and an other example of pleomorphic adenoma in breast cancer patients.
