The Post-transplant Lymphoproliferative Disorder after Renal Transplantation.
- Author:
Kyung Hoon PAIK
1
;
Hee Gyung KANG
;
Won Seog KIM
;
Keon Hee YOO
;
Doo Ryeon CHUNG
;
Suk Koo LEE
Author Information
1. Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
- Publication Type:Review
- Keywords:
Post-transplant lymphoproliferative disorder;
Epstein-Barr virus;
Renal transplantation
- MeSH:
B-Lymphocytes;
Herpesvirus 4, Human;
Immunosuppression;
Kidney Transplantation;
Lymphoproliferative Disorders;
T-Lymphocytes;
Transplants
- From:The Journal of the Korean Society for Transplantation
2008;22(1):21-28
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Post-transplant lymphoproliferative disorder (PTLD) is a B cell proliferative disorder that is associated with Eptstein-Bar (EBV). This is a heterogeneous group of conditions characterized by EBV-driven proliferation of B-lymphocytes in the face of impaired T-cell immune surveillance. While new treatment modalities are being tried with variable success, regular EBV surveillance and carefully monitored reduction of immunosuppression remain the mainstay of treatment. This paper reviews the current knowledge of this increasingly common complications in renal transplant recipients.
