Pathologic Complete Remission in a Patient with Locally Advanced Unresectable Intrahepatic Cholangiocarcinoma Treated with Chemotherapy.
10.15279/kpba.2017.22.4.188
- Author:
Hyo Jun YANG
1
;
Ji Kon RYU
;
Woo Hyun PAIK
;
Sang Hyub LEE
;
Yong Tae KIM
;
Kyoungbun LEE
Author Information
1. Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, Korea. jkryu@snu.ac.kr
- Publication Type:Case Report
- Keywords:
Bile duct cancer;
Cholangiocarcinoma;
Chemotherapy
- MeSH:
Abdominal Pain;
Bile Duct Neoplasms;
Bile Ducts;
Cholangiocarcinoma*;
Cisplatin;
Diagnosis;
Drug Therapy*;
Dyspepsia;
Female;
Hepatectomy;
Humans;
Middle Aged;
Neoplasm, Residual;
Pathology;
Portal Vein;
Recurrence
- From:Korean Journal of Pancreas and Biliary Tract
2017;22(4):188-192
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A 54-year-old female with postprandial dyspepsia and abdominal pain was diagnosed as locally advanced unresectable intrahepatic cholangiocarcinoma by radiologic imaging studies resulting in invasion to bilateral main bile duct and right portal vein. The patient underwent extended right hepatectomy and portal vein resection after gemcitabine and cisplatin combined chemotherapy for a total of 40 cycles after the diagnosis. Final pathology showed, followed by pathological complete remission, without any residual cancer cell. The patient has survived for over 6 years without any evidence of recurrence. This case suggests that locally advanced intrahepatic cholangiocarcinoma, which can't be resected, was also proved to be capable of pathological complete remission with active chemotherapy, and long-term survival could be achieved. Therefore, active multidisciplinary approach and patient-oriented treatments using various methods should be considered for locally advanced unresectable intrahepatic cholangiocarcinoma.
