Obstructive Jaundice due to Biliary Cast Syndrome Followed by Orthotopic Liver Transplantation.
- Author:
Sang Hyun BAK
1
;
Ho Soon CHOI
;
Sun Young YANG
;
Dae Won JUN
;
Sung Hee HAN
;
Hang Lak LEE
;
Oh Young LEE
;
Byung Chul YOON
;
Jun Soo HAHM
;
Min Ho LEE
;
Dong Hoo LEE
;
Choon Suhk KEE
Author Information
1. Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea. choihs@hanyang.ac.kr
- Publication Type:Case Report ; English Abstract
- Keywords:
Biliary cast;
Liver transplantation
- MeSH:
Adult;
Bile Duct Diseases/*complications/diagnosis/etiology;
Female;
Humans;
Jaundice, Obstructive/*etiology;
Liver Transplantation/*adverse effects;
Male;
Middle Aged;
Retrospective Studies;
Syndrome
- From:The Korean Journal of Gastroenterology
2006;48(2):119-123
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Biliary complication occurs in 6-34% of all liver transplant patients. Although bile leaks and strictures are relatively common, other biliary complications such as T-tube leak, choledocholithiasis, and biliary cast syndrome can also be observed. The biliary cast syndrome describes the presence of casts causing obstruction with its resultant sequelae of biliary infection, hepatocyte damage secondary to bile stasis and ductal damage, all contributing to cholangiopathy. Because the exact timing of cast formation after orthotopic liver transplantation is not consistent, it is difficult to define the true incidence of biliary cast syndrome without long-term follow-up data. Proposed etiological mechanisms include acute cellular rejection, prolongation of cold ischemic time, infection, biliary drainage tubes, and biliary obstruction. The diagnosis of biliary cast syndrome is usually confirmed by endoscopic retrograde cholangiopancreatography. There have been few published articles about biliary casts in Korea. Herein, we report a case of biliary cast syndrome followed by orthotopic liver transplantation.
