Local Control after Radiation Therapy for T1-T2 Glottic Carcinoma.
- Author:
Byung Hyun KWON
1
;
Dong Won KIM
Author Information
1. Department of Radiation Therapy, Pusan National University Hospital, Dusan, Korea.
- Publication Type:Original Article
- Keywords:
glottic carcinoma;
radiation therapy;
local control
- MeSH:
Busan;
Female;
Humans;
Larynx;
Male;
Radiotherapy;
Recurrence;
Survival Rate;
Survivors
- From:Journal of the Korean Society for Therapeutic Radiology
1994;12(3):331-336
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To assess the effectiveness and problems of the primary radiation therapy and salvage surgery in a series of patients affected by T1-T2 NO glottic cancers treated from 1985 to 1991 at the Pusan National University Hospital. MATERIALS AND METHODS: From 8.85 to 12/91, 34 patients affected by early glottic carcinoma histologically proven were treated with curative radiation therapy. Distribution of patients according to T stage was 30 for T1 and 4 T2. Male to female ratio was 33:1. Age of patients ranged from 31 to 73 with mean age of 58 years. All of the patients were treated with radical radiation with total tumor dose of 63-75. 3 Gy(median 68.2 Gy), of 5 weekly fractions of 1.8-2Gy and with 6MV photon beams through two laterally opposed fields. RESULTS: The overall 5-year local control rates were 74%(8/30) for T1, and 25%(3/4) for T2. The main cause of failure was progression or recurrence in T(10/11). One failures were observed in T and N at the same time. Of these 11 patients, 9(81%) were salvaged with surgery. After surgical salvage of radiation failures, the 5-year survival rates were 96% for T1 and 75% T2. Among the survivors, 73% of T1 and 33% of T2 were able to preserve the larynx. CONCLUSION: It can be concluded that radiotherapy is the first choice in the treatment of glottic T1 carcinoma.
