A Case of Kaposi's Sarcoma Associated with Castleman's Disease.
- Author:
Hee Ryung CHO
1
;
Chun Pill CHOI
;
Ik Joon KANG
;
Tae Ho CHO
;
Choong Rim HAW
Author Information
1. Department of Dermatology, College of Medicine, Kyung Hee University, Seoul, Korea. crhaw@khmc.or.kr
- Publication Type:Case Report
- Keywords:
Castleman's disease;
Human herpesvirus 8;
Kaposi's sarcoma
- MeSH:
Dermatology;
Giant Lymph Node Hyperplasia*;
Herpesvirus 8, Human;
Humans;
Hyperplasia;
Lymphoproliferative Disorders;
Middle Aged;
Plasma Cells;
Prednisolone;
Sarcoma, Kaposi*;
Skin
- From:Korean Journal of Dermatology
2006;44(8):976-979
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Castleman's disease, also known as angiofollicular lymphoid hyperplasia or giant lymph-node hyperplasia, is an unusual form of a lymphoproliferative disorder, and is divided clinically into a solitary and a multicentric form. The multicentric form of Castleman's disease is almost always of the plasma cell type. This can coexist with Kaposi's sarcoma in some cases. Kaposi's sarcoma is a multicentric, proliferative, vascular tumor involving cutaneous and visceral tissue. Iatrogenically-developed, immunosuppression-associated Kaposi's sarcoma is usually the result of immunosuppressive therapy. A 61-year-old man diagnosed as the plasma cell type of Castleman's disease, who had been treated with prednisolone for 2 years, was referred to the department of dermatology with numerous skin lesions consisting of confluent, violaceous-colored papules and plaques on his palm and soles. Histologic examination of the cutaneous lesions showed consistency with Kaposi's sarcoma. We report a rare case of Kaposi's sarcoma associated with multicentric Castleman's disease.
