Percutaneous Treatment of Renal Cysts with OK-432 Sclerosis.
10.3349/ymj.2007.48.2.270
- Author:
Young Deuk CHOI
1
;
Soung Yong CHO
;
Kang Su CHO
;
Dong Hoon LEE
;
Seung Hwan LEE
Author Information
1. Department of Urology, Yonsei University College of Medicine, Seoul, Korea. youngd74@yumc.yonsei.ac.kr
- Publication Type:Original Article
- Keywords:
Renal cyst;
percutaneous sclerotherapy;
OK-432
- MeSH:
Treatment Outcome;
*Sclerotherapy/adverse effects;
Picibanil/*therapeutic use;
Middle Aged;
Male;
Kidney Diseases, Cystic/pathology/*therapy;
Humans;
Functional Laterality;
Female;
Aged;
Adult
- From:Yonsei Medical Journal
2007;48(2):270-273
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: The aim of this study was to demonstrate OK- 432 sclerotherapy efficacy for treatment of simple renal cysts. MATERIALS AND METHODS: Twenty patients with 25 symptomatic or large simple cysts were treated by ultrasonography (US)-guided percutaneous aspiration and injection of OK-432 (8 men and 12 women, mean age 63.6 years, SD 9.5). Six patients presented with flank pain, 14 presented with renal mass; renal cyst location was right, left, or bilateral sided in 9, 8, and 8 kidneys, respectively. Patients were evaluated by clinical assessment, US, or CT scan 3 months following the procedure. Complete and partial success was defined as symptom resolution with either total cyst ablation or greater than 70% reduction, respectively. Failure was defined as 30% of cyst size recurrence and/or persistent symptoms. RESULTS: Average reduction was 93.0%. Complete and partial resolution occurred in 11 (44.0%) and 13 (52.0%) cysts, respectively. One case was defined as failure, with a 64.2% size reduction from 10.9cm to 3.9cm (volume reduction rate 95.4%). Renal pain improved in all patients, regardless of complete or partial resolution. Minor complications occurred in 3 patients, 2 developed leukocytosis and 1 had mild fever (< 38.5 degrees C) following aspiration and sclerotherapy. Successful treatment was achieved with conservative measures and NSAID therapy. CONCLUSION: Percutaneous treatment of simple renal cysts with OK-432 sclerotherapy was found to be a safe, effective and minimally invasive procedure.
