Black Cohosh and St. John's Wort (GYNO-Plus(R)) for Climacteric Symptoms.
10.3349/ymj.2007.48.2.289
- Author:
Da Jung CHUNG
1
;
Hye Yeon KIM
;
Ki Hyun PARK
;
Kyung Ah JEONG
;
Sung Ki LEE
;
Yu Il LEE
;
Sung Eun HUR
;
Min Sun CHO
;
Byung Seok LEE
;
Sang Wook BAI
;
Cheong Mee KIM
;
Si Hyun CHO
;
Ju Youn HWANG
;
Joo Hyun PARK
Author Information
1. Department of Obstetrics and Gynecology, Yonsei University College of Medicine, Seoul, Korea. kh8730@yumc.yonsei. ac.kr
- Publication Type:Original Article ; Multicenter Study ; Randomized Controlled Trial
- Keywords:
Black cohosh;
St. John's wort;
climacteric symptoms
- MeSH:
Plant Extracts/*therapeutic use;
Placebos;
*Phytotherapy;
*Perimenopause;
Middle Aged;
*Hypericum;
Humans;
Hot Flashes/*prevention & control;
Female;
Estrogens/blood;
Double-Blind Method;
*Cimicifuga
- From:Yonsei Medical Journal
2007;48(2):289-294
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: This study was conducted to investigate the efficacy of black cohosh (Cimicifuga racemosa) and St. John's wort (Hypericum perforatum) in women with climacteric symptoms, and to assess their effects on vaginal atrophy, hormone levels, and lipid profiles. MATERIALS AND METHODS: In this double-blind randomized, placebo-controlled, multicenter study, 89 peri- or postmenopausal women experiencing climacteric symptoms were treated with St. John's wort and black cohosh extract (Gynoplus