Acute Marchiafava-Bignami Disease: Diffusion-Weighted MRI in Cortical and Callosal Involvement.
10.3349/ymj.2007.48.2.321
- Author:
Yon Kwon IHN
1
;
Seong Su HWANG
;
Young Ha PARK
Author Information
1. Department of Radiology, St. Vincent Hospital, The Catholic University of Korea, Gyenggi-do, Korea. Ihn@catholic.ac.kr
- Publication Type:Case Report
- Keywords:
Marchiafava-Bignami disease;
magnetic resonance (MR);
diffusion
- MeSH:
Middle Aged;
Male;
Humans;
Demyelinating Diseases/*pathology;
Corpus Callosum/*pathology;
Brain/*pathology;
Alcoholism/complications
- From:Yonsei Medical Journal
2007;48(2):321-324
- CountryRepublic of Korea
- Language:English
-
Abstract:
Marchiafava-Bignami disease (MBD) is a fatal disorder characterized by demyelination of the corpus callosum. MRI, suggestive of corpus callosum demyelination with associated white matter involvement in both cerebral hemispheres, indicates a diagnosis of MBD. In this case, MR diffusion-weighted findings taken at an acute stage of MBD revealed lesions not only in the corpus callosum but also in the cerebral cortex. Lower apparent diffusion coefficient values of the corpus callosum and cortical lesions were associated with poor clinical outcome.
