Two Cases of Bullous Systemic Lupus Erythematosus.
- Author:
Ho Sun JANG
1
;
Chang Keun OH
;
Kyung Sool KWON
;
Ju Hyun JO
;
Moon Bum KIM
Author Information
1. Department of Dermatology, College of Medicine, Pusan National University Pusan, Korea. kwonks@pusan.ac.kr
- Publication Type:Case Report
- Keywords:
Bullous systemic lupus erythematosus
- MeSH:
Blister;
Humans;
Immunoglobulin G;
Lupus Erythematosus, Systemic*;
Lupus Nephritis;
Neutrophil Infiltration
- From:Korean Journal of Dermatology
2002;40(3):281-285
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Bullous systemic lupus erythematosus (bullous SLE) is an uncommon, distinctive clinical variant of systemic lupus erythematosus (SLE), histopathologically characterized by subepidermal blisters with neutrophil infiltration and immunopathologically linear IgG depositon at the dermoepidermal junction. A blistering eruption may occur during flares of SLE such as lupus nephritis. We report two cases of bullous SLE, confirmed by the clinical, histopathological and immunopathological features. In one patient who has been diagnosed as SLE with diffuse proliferative lupus nephritis (WHO class IV), a blistering eruption occurred during the course of treatment of SLE. In the other patient, the bullous eruption was the initial manifestation of SLE and then she was diagnosed as SLE. We review the recent literature and describe the distinctive features of this rare disorder.
