Primary Sebaceous Carcinoma of the Corneaoscleral Limbus With Pagetoid Recurrence.
10.3341/kjo.2009.23.2.104
- Author:
Sang Jun PARK
1
;
Won Ryang WEE
;
Jin Hak LEE
;
Mee Kum KIM
Author Information
1. Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea. kmk9@snu.ac.kr
- Publication Type:Case Report
- Keywords:
Sebaceous carcinoma;
Limbus;
Conjunctiva;
Pagetoid recurrence;
Mitomycin C
- MeSH:
Adenocarcinoma, Sebaceous/*pathology/surgery;
Biological Dressings;
Diagnosis, Differential;
Eye Neoplasms/*pathology/surgery;
Follow-Up Studies;
Humans;
Limbus Corneae/*pathology;
Male;
Middle Aged;
*Neoplasm Recurrence, Local;
Ophthalmologic Surgical Procedures/methods;
Sebaceous Gland Neoplasms/*pathology/surgery
- From:Korean Journal of Ophthalmology
2009;23(2):104-107
- CountryRepublic of Korea
- Language:English
-
Abstract:
We report a sebaceous carcinoma confined to the corneoscleral limbus without involvement of the eyelid. A 60-year-old man, who showed multiple masses on the corneaoscleral limbus and limbal ulceration but with normal eyelids, underwent surgical en-bloc excision of the masses. Histopathologic examination revealed a sebaceous carcinoma. Three weeks after excision, multiple pagetoid recurrences were found along the bulbar conjunctiva 2 mm away from the limbus. After the application of topical mitomycin C, the pagetoid spread regressed completely. After a 2 year follow-up, no other local or systemic recurrences were observed. This report shows that the ulcerative mass which is confined to only the corneoscleral limbus may be a sebaceous carcinoma even without eyelid involvement. Topical mitomycin C may be effective for treating pagetoid spread of sebaceous carcinoma of limbal origin.
