A Case of Treatment of Delayed Encephalopathy after Acute Carbon Monoxide Intoxication.
- Author:
Sun Hee LEE
1
;
Jin Hyeong JHOO
Author Information
1. Department of Psychiatry, Kangwon National University Hospital, Chuncheon, Korea. jhoojh@kangwon.ac.kr
- Publication Type:Case Report
- Keywords:
Carbon monoxide;
Encephalopathy;
Treatment
- MeSH:
Aphasia;
Behavioral Symptoms;
Brain Diseases*;
Carbon Monoxide*;
Carbon*;
Cognition;
Cognition Disorders;
Female;
Glycerylphosphorylcholine;
Humans;
Memantine;
Middle Aged;
Problem Behavior;
Prognosis;
Rehabilitation
- From:Journal of Korean Geriatric Psychiatry
2017;21(1):41-45
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Delayed carbon monoxide (CO) encephalopathy patients can show cognitive impairment, aphasia, affective and personality changes and behavioral symptoms. The prognosis of them is sometimes poor or irreversible. We present a case of 61-year-old woman who visited us at 56 days after CO intoxication and showed moderate to severe cognitive impairment and behavioral problems. We prescribed the donepezil (5 mg/d), memantine (5 mg/d), choline alfoscerate (800 mg/d) and ziprasidone (20 mg/d), based on previous case reports and performed the cognitive rehabilitation. After 30 days treatment in hospital, she showed dramatic improvement in cognitive functions and behavioral problems. This case suggests that adequate pharmacological and cognitive treatment could improve the moderate to severe symptoms of delayed CO encephalopathy even about 2 months later after CO intoxication.
