In-vivo Proton Magnetic Resonance Spectroscopy in Adnexal Lesions.
- Author:
Seong Whi CHO
1
;
Soon Gu CHO
;
Jung Hee LEE
;
Hyung Jin KIM
;
Myung Kwan LIM
;
Jong Hwa KIM
;
Chang Hae SUH
Author Information
- Publication Type:Original Article ; Research Support, Non-U.S. Gov't
- Keywords: Magnetic resonance (MR), spectroscopy; Ovary, MR; Ovary, neoplasms
- MeSH: Adnexal Diseases/*diagnosis; Adult; Aged; Cystadenoma, Mucinous/diagnosis; Diagnosis, Differential; Female; Human; Magnetic Resonance Spectroscopy/*diagnostic use; Middle Age; Ovarian Neoplasms/diagnosis; Protons; Support, Non-U.S. Gov't; Teratoma/diagnosis; Uterine Neoplasms/diagnosis
- From:Korean Journal of Radiology 2002;3(2):105-112
- CountryRepublic of Korea
- Language:English
- Abstract: OBJECTIVE: To explore the in-vivo 1H- MR spectral features of adnexal lesions and to characterize the spectral patterns of various pathologic entities. MATERIALS AND METHODS: Thirty-one patients with surgically and histopathologically confirmed adnexal lesions underwent short echo-time STEAM (stimulated echo acquisition method) 1H- MR spectroscopy, and the results obtained were analysed. RESULTS: The methylene present in fatty acid chains gave rise to a lipid peak of 1.3 ppm in the 1H- MR spectra of most malignant tumors and benign teratomas. This same peak was not observed, however, in the spectra of benign ovarian epithelial tumors: in a number of these, a peak of 5.2 ppm, due to the presence of the olefine group (-CH=CH-) was noted. The ratios of lipid peak at 1.3 ppm to water peak (lipid/water ratios) varied between disease groups, and in some benign teratomas was characteristically high. CONCLUSION: An intense lipid peak at 1.3 ppm is observed in malignant ovarian tumors but not in benign epithelial tumors. 1H- MRS may therefore be helpful in the differential diagnosis of adnexal lesions.
