Secondary Amyloidosis Associated with Multiple Sclerosis.
- Author:
Seok Jae KANG
1
;
Joo Hark YI
;
Hyun Seok HONG
;
Si Hyung JANG
;
Moon Hyang PARK
;
Ho Jung KIM
;
Kyu Yong LEE
;
Young Joo LEE
;
Sang Woong HAN
;
Seong Ho KOH
Author Information
- Publication Type:Case Report
- Keywords: multiple sclerosis; secondary amyloidosis; nephrotic syndrome
- MeSH: Adult; Amyloidosis; Biopsy; Central Nervous System; Communicable Diseases; Demyelinating Diseases; Edema; Female; Humans; Hypoalbuminemia; Lower Extremity; Multiple Sclerosis; Nephrotic Syndrome; Proteinuria; Quadriplegia
- From:Journal of Clinical Neurology 2009;5(3):146-148
- CountryRepublic of Korea
- Language:English
- Abstract: BACKGROUND: Multiple sclerosis (MS) is a demyelinating disease of the central nervous system. Secondary amyloidosis can occur as a complication of chronic systemic inflammatory and infectious diseases. Until now there has been no report of secondary amyloidosis associated with MS. We report herein a case of renal biopsy-proven secondary amyloidosis in a patient with MS. CASE REPORT: A 41-year-old woman with MS was hospitalized due to aggravated quadriparesis and edema in both lower extremities. Laboratory findings showed nephrotic-range proteinuria and hypoalbuminemia. A percutaneous renal biopsy procedure was performed, the results of which revealed secondary amyloid-A-type amyloidosis associated with MS. CONCLUSIONS: This is the first report of secondary amyloidosis associated with MS.
