Acute Necrotizing Pancreatitis during L-asparaginase Treatment in a Patient with Acute Lymphoblastic Leukemia.
10.15279/kpba.2015.20.4.222
- Author:
Ji Ae LEE
1
;
Hyo Jung KIM
;
Jae Seon KIM
;
Jung Min LEE
;
Ji Eun KIM
;
Sang Youn LIM
;
Seong Min KIM
;
Yeon Ho LEE
Author Information
1. Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea. hjkimmd@korea.ac.kr
- Publication Type:Case Report
- Keywords:
L-asparaginase;
Acute lymphoblastic leukemia;
Acute pancreatitis;
Pseudocyst;
Pancreatic duct leak
- MeSH:
Adult;
Drainage;
Humans;
Octreotide;
Pancreatic Ducts;
Pancreatitis;
Pancreatitis, Acute Necrotizing*;
Precursor Cell Lymphoblastic Leukemia-Lymphoma*
- From:Korean Journal of Pancreas and Biliary Tract
2015;20(4):222-227
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
L-asparaginase is an important component of antileukemic therapy in patients with acute lymphoblastic leukemia. The degree of L-asparaginase toxicity is variable. Several cases of L-asparaginase related pancreatitis have been reported in the literature. However, necrotizing pancreatitis in adult has not been reported yet. Herein, we present a case of necrotizing pancreatitis caused by L-asparaginase that was complicated by pancreatic duct leakage and pseudocyst formation, but successfully treated with percutaneous drainage and octreotide treatment.
