The Effectiveness of Visual Field C10-2 in the Early Detection of Glaucoma with Parafoveal Scotoma.
10.3341/jkos.2017.58.3.321
- Author:
Bo Een HWANG
1
;
Hae Young Lopilly PARK
;
Chan Kee PARK
Author Information
1. Department of Ophthalmology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea. lopilly@hanmail.net
- Publication Type:Original Article
- Keywords:
C10-2;
Early glaucoma;
Optical coherence tomography;
Parafoveal scotoma;
Structure-function analysis
- MeSH:
Ganglion Cysts;
Glaucoma*;
Humans;
Optic Nerve Diseases;
Scotoma*;
Tomography, Optical Coherence;
Visual Field Tests;
Visual Fields*
- From:Journal of the Korean Ophthalmological Society
2017;58(3):321-326
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To identify the correspondence between the central sensitivity of several visual field (VF) tests and ganglion cell inner plexiform layer (GC-IPL) thickness in early glaucoma patients with parafoveal scotoma. METHODS: Fifty-seven eyes from 57 patients with glaucomatous optic neuropathy and parafoveal scotoma were analyzed using the standard automated perimetry (SAP) C10-2 test, the SAP C24-2 test, and the frequency doubling technology perimetry (FDT) C24-2 test. The correlation between the VF central sensitivity and the GC-IPL thickness from macular scans via optical coherence tomography was analyzed. RESULTS: The central sensitivity was 27.51 ± 5.43 dB, 27.39 ± 5.05 dB, and 22.09 ± 5.08 dB for SAP C24-2, SAP C10-2, and FDT C24-2, respectively. Mean GC-IPL thickness was 70.2 ± 8.5 µm. Using regression analysis, the value of log R² between the logarithmic central sensitivity and GC-IPL thickness was 0.498, and the linear R2 between the antilogarithmic central sensitivity and GC-IPL thickness in SAP C10-2 was 0.486, and both were statistically significant (p < 0.05). This relationship was stronger in early glaucoma patients compared to late glaucoma patients using SAP C10-2. CONCLUSIONS: The structure-function relationship between GC-IPL thickness and central sensitivity was better with SAP C10-2, especially in early glaucoma patients, compared to other VF modalities.
