Time Variance of Electrocardiographic Transmural Dispersion in Acute Myocardial Infarction.
10.18501/arrhythmia.2016.030
- Author:
Jin Sun PARK
1
;
Gyo Seung HWANG
;
Sun Mi KIM
;
Kyoung Woo SEO
;
Byoung Joo CHOI
;
So Yeon CHOI
;
Myeong Ho YOON
;
Joon Han SHIN
;
Seung Jea TAHK
Author Information
1. Department of Cardiology, Ajou University School of Medicine, Suwon, Republic of Korea. hwanggs@medimail.co.kr
- Publication Type:Original Article
- Keywords:
Myocardial Infarction;
Cardiac Arrhythmia
- MeSH:
Arrhythmias, Cardiac;
Electrocardiography*;
Humans;
Myocardial Infarction*;
Percutaneous Coronary Intervention
- From:International Journal of Arrhythmia
2016;17(4):174-180
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND AND OBJECTIVES: The mechanism responsible for lethal ventricular arrhythmia (LVA) after acute myocardial infarction (AMI) remains unclear. SUBJECTS AND METHODS: The corrected QT interval (QTc) and interval from the peak to the end of the T wave (TpTe) were measured, which indicated myocardial transmural dispersion of repolarization (TDR) in 72 patients with AMI. TpTe was also expressed as a corrected value, [TpTe/QTe]x100% and TpTe/√RR. These parameters were obtained from all the 12-leads of electrocardiography after arrival at the hospital, just before and after percutaneous coronary intervention (PCI), and at 4, 24, and 48 hours and 5 days after PCI. RESULTS: Analyzing with repeated measures analysis of variance, the TpTe, [TpTe/QTe]x100% and TpTe/√RR after AMI showed significant changes in time variance. The patients were divided into LVA (17 patients, 24%) and non-LVA group (55 patients, 76%). The [TpTe/ QTe]×100% (V₂: 25±7% vs. 22±5%, p=0.036) and TpTe/√RR (V₂: 109 ± 42 ms vs. 88 ± 22 ms, p=0.05, V₃: 108±39 ms vs. 91±27 ms, p=0.048) in V₂ and V₃ leads were prolonged in the LVA group after PCI. The [TpTe/QTe]×100% (28±9 % vs. 22±5%, p=0.025) and TpTe/√RR (129±53 ms vs. 99±41 ms, p=0.05) in V₃ lead were prolonged in the LVA group 24 hours after PCI. CONCLUSION: The mechanisms responsible for LVA after AMI may be associated with increased TDR, and PCI may have an important role in reducing LVA.
