Proton-Pump Inhibitor-Induced Hypocalcemia and Hypomagnesemia.
10.6065/apem.2012.17.4.249
- Author:
Sae Rom CHOI
1
;
Jung Hee BYUN
;
Ah Reum KWON
;
Ye Jin KIM
;
Yong Hyuk KIM
;
Hyun Wook CHAE
;
Ho Seong KIM
Author Information
1. Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea. kimho@yuhs.ac
- Publication Type:Case Report
- Keywords:
Hypoparathyroidism;
Proton-pump inhibitors;
Hypocalcemia
- MeSH:
2-Pyridinylmethylsulfinylbenzimidazoles;
Calcium;
Calcium Gluconate;
Cholecalciferol;
Emergencies;
Female;
Gluconates;
Humans;
Hypocalcemia;
Hypoparathyroidism;
Infant, Newborn;
Magnesium Sulfate;
Parathyroid Hormone;
Phenobarbital;
Proton Pumps;
Seizures;
Vitamin D
- From:Annals of Pediatric Endocrinology & Metabolism
2012;17(4):249-252
- CountryRepublic of Korea
- Language:English
-
Abstract:
A 7-day-old female neonate who visited emergency depar tment due to generalized tonic seizure. Laboratory test results showed hypocalcemia (5.7 mg/dL), hypomagnesemia (0.55 mmol/L), low parathyroid hormone (7.5 pg/mL), and normal 25(OH) vitamin D3. Symptom and metabolic abnormalities were normalized with intravenous calcium gluconate and magnesium sulfate. Discharged with supplement of oral calcium, vitamin D, phenobarbital, and lansoprazol, she was re-admitted with hypocalcemia (4.8 mg/dL) with normal level of parathyroid hormone (12.3 pg/mL). Hypocalcemia was resolved with discontinuation of proton pump inhibitor. We report a case of recurrent hypocalcemia and hypomagnesemia due to proton-pump inhibitor.
