Comparison of Blood Donor Reactions in Whole Blood Donations, Plasmapheresis and Plateletpheresis.
- Author:
Sung Yun CHO
1
;
Jun Seok LEE
;
Hyoun Sook SEO
;
Sang Geun ROH
;
Jai Ho WEE
Author Information
1. Busan Blood Center, Korea Red Cross, Busan, Korea. jhwez@redcross.or.kr
- Publication Type:Original Article
- Keywords:
Blood donation;
Plasmapheresis;
Plateletpheresis;
Vasovagal reaction
- MeSH:
Blood Component Removal;
Blood Donors;
Citric Acid;
Female;
Hematoma;
Humans;
Male;
Plasmapheresis;
Plateletpheresis;
Red Cross;
Tissue Donors
- From:Korean Journal of Blood Transfusion
2009;20(1):55-60
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Several kinds of adverse reactions can occur during blood donation such as vasovagal reaction (VVR), hematoma, citrate toxicity, etc. These adverse reactions are not common, but they are important because they cause a decrease in re-donation. The cost for maintaining a repeat donation is very low compared to that for securing first-time donors. Whole blood donation differs from apheresis in some aspects, and this could have an influence on blood donor reactions. We compared whole blood donation with apheresis for blood donor reactions. METHODS: From January to December in 2007 at Busan Red Cross Blood Center, 109,004 donations were investigated for blood donor reactions. 76,098 (69.8%) donations were from male donors and 32,906 (30.2%) were from females. 77,813 (71.3%) donations were for whole blood, 25,224 (23.2%) were for plasmapheresis and 5,967 (5.5%) were for plateletpheresis. RESULTS: The frequencies of VVR were 0.10% (75/77,813) for the whole blood donations, 0.15% (37/25,224) for plasmapheresis and 0.03% (2/5,967) for plateletpheresis (P<0.05). The frequency of hematoma was 0.05% (37/77,813) for whole blood donation, 0.25% (62/25,224) for plasmapheresis and 0.27% (16/5,967) for plateletpheresis (P<0.05). Citrate toxicity was extremely rare. VVR was most common in plasmapheresis, and it was rare in plateletpheresis. CONCLUSION: The kinds of donated blood components had an influence on blood donor reactions. Understanding these characteristics helps to prevent adverse reaction. Having people re-donate is essential for keeping a large sized donor pool. So, appropriate management to prevent donor reactions is very important.
