A Case of CD30 Positive ALK-Negative Systemic Anaplastic Large Cell Lymphoma Involving Bone Marrow.
- Author:
Yong Hwan LEE
1
;
Soo Ho KIM
;
Moo Kyu SUH
;
Tae Jung JANG
Author Information
1. Department of Dermatology, College of Medicine, Dongguk University, Gyeongju, Korea. smg@dongguk.ac.kr
- Publication Type:Case Report
- Keywords:
Anaplastic large cell lymphoma;
Bone marrow involvement
- MeSH:
Antigens, CD30;
Bone Marrow*;
Classification;
Lymphoma, Large-Cell, Anaplastic*;
Lymphoma, Non-Hodgkin;
Lymphoproliferative Disorders;
Mast Cells;
T-Lymphocytes;
Thigh;
World Health;
World Health Organization
- From:Korean Journal of Dermatology
2007;45(7):687-691
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
CD 30 positive anaplastic large cell lymphoma (ALCL) is a type of non-Hodgkin's lymphoma, a tumor that is composed of mostly mast cells expressing CD30 antigens. According to the 2005 World Health Organization-European Organization for Research and Treatment of Cancer (WHO-EORTC) classification, it can be classified as systemic ALCL and primary cutaneous CD30 positive T-cell lymphoproliferative disorder. Systemic ALCL can be subclassified into ALK positive and negative. There have been many cases of primary cutaneous CD30 positive T-cell lymphoproliferative disorder, but reports of systemic ALCL have been rare. We report a case of CD30 positive/ALK negative systemic anaplastic large cell lymphoma involving bone marrow in a 51 year-old-male who showed two pruritic, 1.5x1.0x0.8 cm and 1.0x0.5x0.4 cm sized, erosive, erythematous nodules on the right thigh and calf.
