One case of Lynch type II syndrome.
- Author:
Kyongjin KIM
1
;
Nam Eui KIM
;
Yongho LEE
;
Kyounga KIM
;
Sangki HONG
;
Sukyung BAEK
;
Myungjin JOO
Author Information
1. Department of Obstetrics and Gynecology, Presbyterian Medical center, Jeon-ju, Korea. kyungjin_k@hotmail.com
- Publication Type:Case Report
- Keywords:
Endometrial cancer;
HNPCC;
Colorectal cancer;
MSI (microsatellite instability);
MMR (mismatch repair)
- MeSH:
Colonic Neoplasms;
Colorectal Neoplasms;
Colorectal Neoplasms, Hereditary Nonpolyposis;
DNA Mismatch Repair;
Endometrial Neoplasms;
Endometrium;
Female;
Humans;
Intestine, Small;
Ovary;
Stomach;
Stomach Neoplasms
- From:Korean Journal of Obstetrics and Gynecology
2009;52(11):1164-1168
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Lynch syndrome is also called Hereditary nonpolyposis colorectal cancer (HNPCC). It is characterized by a risk of colorectal cancer and other cancers of the endometrium, ovary, stomach, small intestine etc. The increased risk is due to inherited mutations that impaired DNA mismatch repair. Two to three percentage of colon cancer is caused by Lynch syndrome. A family history of colon cancer occurs at a young age. We experienced one case of Lynch syndrome who had had stomach cancer, endometrial cancer and colon cancer recently. Hence we report this case with a brief review of literature.
