3 Cases of Mononeuropathy Multiplex Associated with Systematic Vasculitis.
- Author:
Byung Jo KIM
1
;
Kun Woo PARK
;
Gwan Gyu SONG
;
Young Ho LEE
;
Seong Beom KOH
;
Jin Hyo HAN
;
Dae Hie LEE
Author Information
1. Department of Neurology, Korea University, College of Medicine.
- Publication Type:Case Report
- MeSH:
Churg-Strauss Syndrome;
Humans;
Immunosuppressive Agents;
Mononeuropathies*;
Neural Conduction;
Peripheral Nerves;
Peripheral Nervous System;
Peripheral Nervous System Diseases;
Plasmapheresis;
Polyarteritis Nodosa;
Prednisolone;
Rheumatoid Vasculitis;
Systemic Vasculitis;
Vasculitis*
- From:Journal of the Korean Neurological Association
1996;14(4):1007-1017
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Peripheral nervous system involvement is common in systemic vasculitis, occurring most frequently in the polyarteritis nodosa (PAN) group of disorders and in rheumatoid vasculitis. Within the polyarteritis nodosa group of systemic necrotizing vasculitides, three subgroups have been described: classic polyarteritis nodosa, Churg-Strauss syndrome, and an overlap syndrome. Three patients with evidence of systemic vasculitis and peripheral neuropathy were clinically and electrophysiologically investigated. All cases presented clinically with mononeuropathy multiples considered typical pattern of ischemic involvement of the peripheral nerve. The causes included polyarteritis nodosa, its Churg-strauss variant, and the overlap syndrome. Pain and weakness were frequent symptoms. Nerve conduction studies were abnormal In all cases. Necrotizing vasculitis was present as pathologic findings in two cases. All patients were treated with prednisolone alone or in combination with other immunosuppressive agents or with plasmapheresis.
