A Case of Clopidogrel-induced Neutropenia in Chronic Renal Failure.
- Author:
Gi Youn HONG
1
;
Han Gyung SEON
;
Joon Gu CHEONG
;
Sae Kyung JOO
;
Min Kyoung KANG
;
Ji Eun LEE
;
Ju Hwan KIM
;
Seung Won KOO
;
Kyoung Mi PARK
;
So Yung LEE
;
Dong Ho YANG
;
Hyung Jong KIM
Author Information
1. Department of Internal Medicine, College of Medicine, CHA University, Seongnam, Korea. khj04@cha.ac.kr
- Publication Type:Case Report
- Keywords:
Clopidogrel;
Neutropenia;
Chronic renal failure
- MeSH:
Adenosine Diphosphate;
Anemia, Aplastic;
Aspirin;
Blood Platelets;
Humans;
Kidney Failure, Chronic;
Myocardial Ischemia;
Neutropenia;
Purpura, Thrombocytopenic;
Pyridines;
Stents;
Thrombocytopenia;
Thrombosis;
Ticlopidine
- From:Korean Journal of Nephrology
2010;29(1):153-157
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Clopidogrel, a thienopyridine derivative, is an anti-platelet agent that acts as an antagonist of the platelet adenosine diphosphate receptor and considered for essential prophylaxis for intracoronary stent thrombosis in the treatment of ischemic heart disease. Clopidogrel is considered as safe as aspirin but a few cases of severe hematologic adverse reactions associated with clopidogrel had been reported such as neutropenia, aplastic anemia, thrombocytopenic purpura, and thrombocytopenia. We report a rare case of neutropenia induced by clopidogrel in chronic renal failure in a patient who underwent percutaneous coronary intervention.
