Effects of perilla oil on plasma concentrations of cardioprotective (n-3) fatty acids and lipid profiles in mice.
- Author:
Keun Hee CHUNG
1
;
Hyo Jeong HWANG
;
Kyung Ok SHIN
;
Woo Min JEON
;
Kyung Soon CHOI
Author Information
- Publication Type:Original Article
- Keywords: Perilla oil; flaxseed oil; (n-3) polyunsaturated fatty acids; DPA; EPA
- MeSH: alpha-Linolenic Acid; Animals; Arachidonic Acid; Eicosapentaenoic Acid; Fatty Acids; Fatty Acids, Monounsaturated; Fatty Acids, Unsaturated; Flax; Linoleic Acid; Linseed Oil; Mice; Models, Animal; Oils; Oleic Acid; Perilla; Plant Oils; Plasma; Vegetables
- From:Nutrition Research and Practice 2013;7(4):256-261
- CountryRepublic of Korea
- Language:English
- Abstract: The aim of this study was to examine the effects of perilla oil as well as several vegetable oils, including flaxseed oil, canola oil, and rice bran oil on plasma levels of cardioprotective (n-3) polyunsaturated fatty acids in mice by feeding each vegetable oil for a period of eight weeks. Concentrations of docosapentaenoic acid (DHA) and eicosapentaenoic acid (EPA), fish-based (n-3) polyunsaturated fatty acids, showed an increase in the plasma of mice fed perilla and flaxseed oils compared to those of mice in the control group (P < 0.05), whereas rice bran and canola oils did not alter plasma DPA and EPA concentrations. Arachidonic acid concentration was increased by feeding rice bran oil (P < 0.05), but not canola, flaxseed, or perilla oil. In addition, oleic acid, linoleic acid, and docosahexaenoic acid concentrations were altered by feeding dietary rice bran, canola, perilla, and flaxseed oils. Findings of this study showed that perilla oil, similar to flaxseed oil, is cardioprotective and could be used as an alternative to fish oil or even flaxseed oil in animal models.
