Clinical Features of Ischemic Colitis in Patients with Chronic Kidney Disease.
- Author:
Su Jin SEOK
1
;
Kyu Jin KIM
;
Bum Suk SON
;
Yong Sub LEE
;
Seong Ah HONG
;
Moo Yong PARK
;
Soo Jeong CHOI
;
Bong Min KO
;
Jin Kuk KIM
;
Seung Duk HWANG
Author Information
1. Department of Internal Medicine, Soonchunhyang University College of Medicine, Bucheon, Korea. medkjk@schbc.ac.kr
- Publication Type:Original Article
- Keywords:
Chronic renal failure;
Ischemic colitis;
Hospitalization
- MeSH:
Cardiovascular Diseases;
Colitis, Ischemic;
Colon;
Dialysis;
Glomerular Filtration Rate;
Hemoglobins;
Hospitalization;
Humans;
Hypertension;
Hypotension;
Kidney;
Kidney Failure, Chronic;
Korea;
Leukocyte Count;
Prevalence;
Renal Dialysis;
Renal Insufficiency, Chronic;
Retrospective Studies;
Vascular Diseases
- From:Korean Journal of Nephrology
2009;28(6):595-602
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: Hemodialysis patients are at an increased risk of ischemic colitis because of accelerated arterial vascular disease rate and hypotension during dialysis. But few data exist on the clinical features of ischemic colitis in patients with chronic kidney disease including dialysis patients in Korea. The aim of this study is to identify the clinical features of ischemic colitis in patients with chronic kidney disease (CKD). METHODS: We retrospectively reviewed total 68 patients (63.9+/-16.2 years) with ischemic colitis. We analyzed medical history, colonoscopic findings, clinical characteristics, and compared them according to kidney function. RESULTS: Twenty-two (33.9%) patients had CKD stage > or =3 at diagnosis of ischemic colitis. Prevalence of hypertension and diabetes was higher in patients with CKD than those with normal kidney function. High leukocyte count and low hemoglobin level were demonstrated at diagnosis in CKD patients. In addition, duration of hospitalization in patients with CKD was longer than patients with normal kidney function. However, there was no significant difference in right colonic involvement, cardiovascular diseases, surgical intervention, and mortality. Hospitalization days was positively correlated with increased leukocyte count (p=0.015) and decreased albumin level (p=0.002), while that was negatively correlated with age-adjusted estimated glomerular filtration rate (p=0.002). CONCLUSION: Ischemic colitis in patients with CKD had longer hospitalization than in those with normal kidney function. However, there was no significant difference in surgical intervention and mortality.
