Immediate hypersensitivity reaction to steroids: a case report.
10.4168/aard.2017.5.3.165
- Author:
Eun Ji KIM
1
;
Kyoung Hee SOHN
;
Jin LEE
;
Dong Yoon KANG
;
Ju Yeun LEE
;
Hye Ryun KANG
Author Information
1. College of Pharmacy, Institute of Pharmaceutical Science and Technology, Hanyang University, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Drug hypersensitivity;
Steroids;
Skin tests
- MeSH:
Adult;
Anaphylaxis;
Angioedema;
Bronchial Spasm;
Dexamethasone;
Drug Hypersensitivity;
Female;
Humans;
Hydrocortisone;
Hypersensitivity;
Hypersensitivity, Immediate*;
Intradermal Tests;
Methylprednisolone;
Recurrence;
Skin;
Skin Tests;
Steroids*;
Triamcinolone;
Urticaria
- From:Allergy, Asthma & Respiratory Disease
2017;5(3):165-168
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Steroids are widely used for the treatment of a variety of diseases, including autoimmune and allergic diseases. Immediate hypersensitivity reactions can occur within 1 hour after administration of steroids and are regarded as IgE-mediated hypersensitivity presenting as urticaria, angioedema, bronchospasm, and anaphylaxis. Steroid hypersensitivity is rare, but can be life-threatening. Therefore, it is important to find implicated drugs and to choose safe alternative agents. A 44-year-old female was diagnosed with steroid hypersensitivity after intralesional steroid injection. She underwent a skin prick test and an intradermal test for methylprednisolone, triamcinolone, hydrocortisone, and dexamethasone. The results were positive to triamcinolone and methylprednisolone. The patient was educated to avoid culprit agents in order to prevent recurrence. Herein, we report a rare case of steroid hypersensitivity that showed positive reactions to triamcinolone and methylprednisolone. A review of the literature for steroid hypersensitivity is also provided.
