A Case of Rh-incompatible Allogeneic Bone Marrow Transplantation: Transplant of E- and c-positive Bone Marrow in a Recipient with Anti-E and Anti-c Antibodies.
- Author:
So Young CHONG
1
;
Hyun Ok KIM
;
Jee Sook HAHN
;
Seok LEE
;
Seong Cheol KIM
;
Nae Choon YOO
;
Yun Woong KO
Author Information
1. Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Rh incompatibility;
Bone marrow transplantation
- MeSH:
Antibodies*;
Blood Group Antigens;
Bone Marrow Transplantation*;
Bone Marrow*;
Hemolysis;
Humans;
Plasma;
Siblings;
Tissue Donors
- From:Korean Journal of Blood Transfusion
1997;8(1):131-137
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The effects of Rh incompatibility in bone marrow transplantation (BMT) has not been studied extensively as ABO incompatibility. But it has been known that Rh incompatibility does not impair the engraftment of donor bone marrow. The recipient's blood groups were AB, DCe, who has anti-E and anti-c in her serum. The sibling donor blood groups were B, DCEce. There was a minor ABO incompatibility and Rh incompatibility due to anti-E and anti-c between donor and recipient. We performed the plasma and RBC depletion of marrow using the cell separator before it was infused. The clinical course after BMT was not eventful except mild delayed hemolysis and delayed hematopoietic recovery, which may be attributable to low marrow cell dose.
