A Case of Photosensitivity Induced by the Hormonal Replacement Agents Containing Estrogen and Progesterone.
- Author:
Ki Woong RO
1
;
Jin Geol JUNG
;
Sang Dai SHIM
;
Myung Hwa KIM
;
Yong Woo CINN
Author Information
1. Department of Dermatology, College of Medicine, Dankook University, Cheonan, Korea. rkw38@intizen.co.kr
- Publication Type:Case Report
- Keywords:
Estrogen;
Photosensitivity;
Progesterone
- MeSH:
Adult;
Contraceptives, Oral;
Erythema;
Estrogens*;
Female;
Hormone Replacement Therapy;
Humans;
Hysterectomy;
Progesterone*;
Skin;
Uterine Cervical Neoplasms
- From:Korean Journal of Dermatology
2005;43(8):1098-1101
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Estrogen and progesterone are widely used in oral contraceptives and hormone replacement therapies and are rarely known to cause a photosensitive reaction. We report a case of photosensitivity induced by the hormonal replacement agents containing estrogen and progesterone. A 36-year-old woman reported a 3-year history of erythematous papules and diffuse erythema on sun-exposed areas. She had taken the hormonal agents for 5 years, following a total abdominal hysterectomy and bilateral salpingo-oophorectomy for cervical cancer. A phototest showed a marked decrease in the minimal erythema dose (MED) of UVA (3J/cm2) and UVB (30mJ/cm2). After the cessation of the hormonal agents, the skin lesions subsided with the disappearance of photosensitivity, and the MED was raised to 5J/cm2(UVA) and 90mJ/cm2 (UVB).